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1

Inflammatory cytokine release of astrocytes in vitro is reduced by all-trans retinoic acid

Sabien van Neerven, Andrei Nemes, Philipp Imholz, Tommy Regen, Bernd Denecke, Sonja Johann, Cordian Beyer, Uwe-Karsten Hanisch, Jörg Mey

Journal:

Journal of Neuroimmunology

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

2

Thrombin-Induced Activation of Cultured Rodent Microglia

Thomas Möller, Uwe-Karsten Hanisch, Bruce R. Ransom

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 287 KB

english, 2000

3

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

Hanisch, Uwe-Karsten, Kettenmann, Helmut

Journal:

Nature Neuroscience

Year:

2007

Language:

english

File:

PDF, 988 KB

english, 2007

4

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

Mildner, Alexander, Schmidt, Hauke, Nitsche, Mirko, Merkler, Doron, Hanisch, Uwe-Karsten, Mack, Matthias, Heikenwalder, Mathias, Brück, Wolfgang, Priller, Josef, Prinz, Marco

Journal:

Nature Neuroscience

Year:

2007

Language:

english

File:

PDF, 1.11 MB

english, 2007

5

Microglial phenotype: is the commitment reversible?

Michal Schwartz, Oleg Butovsky, Wolfgang Brück, Uwe-Karsten Hanisch

Journal:

Trends in Neurosciences

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

6

Toll-like receptors: roles in neuroprotection?

Uwe-Karsten Hanisch, Thomas V. Johnson, Jonathan Kipnis

Journal:

Trends in Neurosciences

Year:

2008

Language:

english

File:

PDF, 521 KB

english, 2008

7

Biochemical analysis of proteasomes from mouse microglia: Induction of immunoproteasomes by interferon-γ and lipopolysaccharide

Ralf Stohwasser, Jan Giesebrecht, Regine Kraft, Eva-Christina Müller, Karl Georg Häusler, Helmut Kettenmann, Uwe-Karsten Hanisch, Peter-M. Kloetzel

Journal:

Year:

2000

Language:

english

File:

PDF, 262 KB

english, 2000

8

Neurotoxicity induced by interleukin-2: Involvement of infiltrating immune cells

Uwe-Karsten Hanisch, Jochen Neuhaus, Rémi Quirion, Helmut Kettenmann

Journal:

Year:

1996

Language:

english

File:

PDF, 2.91 MB

english, 1996

9

Characterization of microglial cells and their response to stimulation in an organotypic retinal culture system

Katharina Mertsch, Uwe-Karsten Hanisch, Helmut Kettenmann, Jutta Schnitzer

Journal:

The Journal of Comparative Neurology

Year:

2001

Language:

english

File:

PDF, 656 KB

english, 2001

10

GFAP promoter-controlled EGFP-expressing transgenic mice: A tool to visualize astrocytes and astrogliosis in living brain tissue

Christiane Nolte, Marina Matyash, Tatjyana Pivneva, Carola G. Schipke, Carsten Ohlemeyer, Uwe-Karsten Hanisch, Frank Kirchhoff, Helmut Kettenmann

Journal:

Year:

2001

Language:

english

File:

PDF, 2.45 MB

english, 2001

11

The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls

Uwe-Karsten Hanisch, Marco Prinz, Klemens Angstwurm, Karl Georg Häusler, Oliver Kann, Helmut Kettenmann, Joerg R. Weber

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

12

FK506 Protects Against Various Immune Responses and Secondary Degeneration Following Cerebral Ischemia

Stephan Brecht, Vicki Waetzig, Ute Hidding, Uwe-Karsten Hanisch, Michael Walther, Thomas Herdegen, Wolfram F. Neiss

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

2009

Language:

english

File:

PDF, 411 KB

english, 2009

13

Microglia as a source and target of cytokines

Uwe-Karsten Hanisch

Journal:

Year:

2002

Language:

english

File:

PDF, 1.07 MB

english, 2002

14

Editorial

Uwe-Karsten Hanisch, Shinichi Kohsaka, Thomas Möller

Journal:

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

15

c-Jun N-terminal kinases (JNKs) mediate pro-inflammatory actions of microglia

Vicki Waetzig, Karen Czeloth, Ute Hidding, Kirsten Mielke, Moritz Kanzow, Stephan Brecht, Mario Goetz, Ralph Lucius, Thomas Herdegen, Uwe-Karsten Hanisch

Journal:

Year:

2005

Language:

english

File:

PDF, 530 KB

english, 2005

16

Lipopolysaccharide is a frequent and significant contaminant in microglia-activating factors

Jonathan R. Weinstein, Sarah Swarts, Caroline Bishop, Uwe-Karsten Hanisch, Thomas Möller

Journal:

Year:

2008

Language:

english

File:

PDF, 343 KB

english, 2008

17

Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype

Denise van Rossum, Sören Hilbert, Silke Straßenburg, Uwe-karsten Hanisch, Wolfgang Brück

Journal:

Year:

2008

Language:

english

File:

PDF, 1000 KB

english, 2008

18

Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia

Anja Hoffmann, Fred Hofmann, Ingo Just, Seija Lehnardt, Uwe-Karsten Hanisch, Wolfgang Brück, Helmut Kettenmann, Gudrun Ahnert-Hilger, Markus Höltje

Journal:

Year:

2008

Language:

english

File:

PDF, 1.14 MB

english, 2008

19

Fibronectin stimulates Escherichia coli phagocytosis by microglial cells

Sandra Ribes, Sandra Ebert, Tommy Regen, Dirk Czesnik, Jörg Scheffel, Andre Zeug, Stephanie Bunkowski, Helmut Eiffert, Uwe-Karsten Hanisch, Sven Hammerschmidt, Roland Nau

Journal:

Year:

2010

Language:

english

File:

PDF, 537 KB

english, 2010

20

Stereotaxic preparation of circumscribed cortical areas from rat brain for biochemical studies

Uwe-Karsten Hanisch, Thomas Rothe, Harry H. Webster, Wolfgang Härtig, Dietmar Biesold

Journal:

Journal of Neuroscience Methods

Year:

1990

Language:

english

File:

PDF, 507 KB

english, 1990

21

Neuroanatomical Localization, Pharmacological Characterization and Functions of CGRP, Related Peptides and Their Receptors

DENISE VAN ROSSUM, UWE-KARSTEN HANISCH, RÉMI QUIRION

Journal:

Neuroscience & Biobehavioral Reviews

Year:

1997

Language:

english

File:

PDF, 8.61 MB

english, 1997

22

Interferon-γ differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages

Karl Georg Häusler, Marco Prinz, Christiane Nolte, Joerg R. Weber, Ralf R. Schumann, Helmut Kettenmann, Uwe-Karsten Hanisch

Journal:

European Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 448 KB

english, 2002

23

Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro

Clemens Boucsein, Robert Zacharias, Katrin Färber, Sanja Pavlovic, Uwe-Karsten Hanisch, Helmut Kettenmann

Journal:

European Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 381 KB

english, 2003

24

Murine Microglial Cells Produce and Respond to Interleukin-18

Marco Prinz, Uwe-Karsten Hanisch

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 454 KB

english, 1999

25

Expression of coagulation factors and their receptors in tumor tissue and coagulation factor upregulation in peripheral blood of patients with cerebral carcinoma metastases

Jan Walter, Linn L. Handel, Michael Brodhun, Denise van Rossum, Uwe-Karsten Hanisch, Lutz Liebmann, Frank Heppner, Roland Goldbrunner, Arend Koch, Susanne A. Kuhn

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2012

Language:

english

File:

PDF, 960 KB

english, 2012

26

A paediatric supratentorial primitive neuroectodermal tumour associated with malignant astrocytic transformation and a clonal origin of both components

Susanne A. Kuhn, Uwe-Karsten Hanisch, Kristian Ebmeier, Christian Beetz, Michael Brodhun, Rupert Reichart, Christian Ewald, Thomas Deufel, Rolf Kalff

Journal:

Neurosurgical Review

Year:

2007

Language:

english

File:

PDF, 458 KB

english, 2007

27

Thrombin-Induced Regulation of CD95(Fas) Expression in the N9 Microglial Cell Line: Evidence for Involvement of Proteinase-Activated Receptor1and Extracellular Signal-Regulated Kinase 1/2

Jonathan R. Weinstein, Matthew Zhang, Mansur Kutlubaev, Richard Lee, Caroline Bishop, Henrik Andersen, Uwe-Karsten Hanisch, Thomas Möller

Journal:

Neurochemical Research

Year:

2009

Language:

english

File:

PDF, 439 KB

english, 2009

28

The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level

Oliver Kann, Anja Hoffmann, Ralf R. Schumann, Joerg R. Weber, Helmut Kettenmann, Uwe-Karsten Hanisch

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 341 KB

english, 2004

29

Unraveling thrombin's true microglia-activating potential: markedly disparate profiles of pharmaceutical-grade and commercial-grade thrombin preparations

Jonathan R. Weinstein, Soyon Hong, John D. Kulman, Caroline Bishop, Jon Kuniyoshi, Henrik Andersen, Bruce R. Ransom, Uwe-Karsten Hanisch, Thomas Möller

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 339 KB

english, 2005

30

Fibronectin is elevated in the cerebrospinal fluid of patients suffering from bacterial meningitis and enhances inflammation caused by bacterial products in primary mouse microglial cell cultures

Miriam Goos, Peter Lange, Uwe-Karsten Hanisch, Marco Prinz, Jörg Scheffel, Reiner Bergmann, Sandra Ebert, Roland Nau

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 838 KB

english, 2007

31

TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes

Anja Hoffmann, Christian Grimm, Robert Kraft, Olaf Goldbaum, Arne Wrede, Christiane Nolte, Uwe-Karsten Hanisch, Christiane Richter-Landsberg, Wolfgang Brück, Helmut Kettenmann, Christian Harteneck

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

32

Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid

Sabien Van Neerven, Tommy Regen, Dhana Wolf, Andrei Nemes, Sonja Johann, Cordian Beyer, Uwe-Karsten Hanisch, Jörg Mey

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 816 KB

english, 2010

33

Microglia

Denise van Rossum, Uwe-Karsten Hanisch

Journal:

Metabolic Brain Disease

Year:

2004

Language:

english

File:

PDF, 127 KB

english, 2004

34

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

Wolfgang Brück, Ramona Pförtner, Trinh Pham, Jingya Zhang, Liat Hayardeny, Victor Piryatinsky, Uwe-Karsten Hanisch, Tommy Regen, Denise van Rossum, Lars Brakelmann, Karin Hagemeier, Tanja Kuhlmann, Ch

Journal:

Acta Neuropathologica

Year:

2012

Language:

english

File:

PDF, 917 KB

english, 2012

35

β-adrenergic receptor stimulation selectively inhibits IL-12p40 release in microglia

Marco Prinz, Karl Georg Häusler, Helmut Kettenmann, Uwe-Karsten Hanisch

Journal:

Year:

2001

Language:

english

File:

PDF, 898 KB

english, 2001

36

CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS

Tommy Regen, Denise van Rossum, Jörg Scheffel, Maria-Eleni Kastriti, Natalia H. Revelo, Marco Prinz, Wolfgang Brück, Uwe-Karsten Hanisch

Journal:

Brain, Behavior, and Immunity

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

37

59 Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype

Denise van Rossum, Sören Hilbert, Silke Straßenburg, Uwe-Karsten Hanisch, Wolfgang Brück

Journal:

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

38

303 Toll-like receptor 4/MyD88 pathway mediates microglial proinflammatory cytokine responses to thrombin-associated coagulation protein complexes

Jörg Scheffel, Denise van Rossum, Jonathan R. Weinstein, Hassan Dihazi, Tommy Regen, Wolfgang Brück, Helmut Kettenmann, Marco Prinz, Thomas Möller, Uwe-Karsten Hanisch

Journal:

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

39

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

Marco Prinz, Hauke Schmidt, Alexander Mildner, Klaus-Peter Knobeloch, Uwe-Karsten Hanisch, Jenni Raasch, Doron Merkler, Claudia Detje, Ilona Gutcher, Jörg Mages, Roland Lang, Roland Martin, Ralf Gold,

Journal:

Year:

2008

Language:

english

File:

PDF, 2.01 MB

english, 2008

40

The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells

Sandra Ribes, Nina Adam, Sandra Ebert, Tommy Regen, Stephanie Bunkowski, Uwe-Karsten Hanisch, Roland Nau

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

41

Microglial activation by TLR ligands: Usual and unusual suspects

Uwe-Karsten Hanisch

Journal:

Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 75 KB

english, 2007

42

Cytoskeletal dynamics in dendritic spines: direct modulation by glutamate receptors?

Denise van Rossum, Uwe-Karsten Hanisch

Journal:

Trends in Neurosciences

Year:

1999

Language:

english

File:

PDF, 7.81 MB

english, 1999

43

Alternative splicing of mouse IL-15 is due to the use of an internal splice site in exon 5

Marco Prinz, Uwe-Karsten Hanisch, Helmut Kettenmann, Frank Kirchhoff

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 525 KB

english, 1998

44

The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells

Ribes, Sandra, Adam, Nina, Schütze, Sandra, Regen, Tommy, Redlich, Sandra, Janova, Hana, Borisch, Angela, Hanisch, Uwe-Karsten, Nau, Roland

Journal:

Journal of Neuroimmunology

Year:

2012

Language:

english

File:

PDF, 847 KB

english, 2012

45

Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin

Smadar Hadas, Maya Spira, Uwe-Karsten Hanisch, Fanny Reichert, Shlomo Rotshenker

Journal:

Journal of Neuroinflammation

Year:

2012

Language:

english

File:

PDF, 475 KB

english, 2012

46

Linking STAT and TLR signaling in microglia: a new role for the histone demethylase Jmjd3

Hanisch, Uwe-Karsten

Journal:

Journal of Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 308 KB

english, 2014

47

Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebralEscherichia coliK1 infection

Ribes, Sandra, Meister, Tanja, Ott, Martina, Redlich, Sandra, Janova, Hana, Hanisch, Uwe-Karsten, Nessler, Stefan, Nau, Roland

Journal:

Journal of Neuroinflammation

Year:

2014

Language:

english

File:

PDF, 511 KB

english, 2014

48

Immunological cross-reactivities between proteins secreted by the subcommissural organ, and plant lectins

Debbage, Paul, Lehmann, Werner, Hanisch, Uwe-Karsten, Naumann, Wilfried W.

Journal:

Acta Histochemica

Year:

1993

Language:

english

File:

PDF, 3.12 MB

english, 1993

49

Empty liposomes induce antitumoral effects associated with macrophage responses distinct from those of the TLR1/2 agonist Pam3CSK4(BLP)

König, Simone, Regen, Tommy, Dittmann, Kai, Engelke, Michael, Wienands, Jürgen, Schwendener, Reto, Hanisch, Uwe-Karsten, Pukrop, Tobias, Hahn, Heidi

Journal:

Cancer Immunology, Immunotherapy

Year:

2013

Language:

english

File:

PDF, 474 KB

english, 2013

50

MyD88 signaling mediates the effects of the innate immune response in cerebellar short-term synaptic plasticity

Barrantes-freer, Alonso, Mortensen, Lena Sünke, Lohrberg, Melanie, Götz, Alexander, Hanisch, Uwe-karsten, Pardo, Luis A., Brück, Wolfgang, Stadelmann-nessler, Christine

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014